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ea0063p617 | Diabetes, Obesity and Metabolism 2 | ECE2019

Liraglutide restores the hyperglycemic oxidative imbalance and induces the expression of CRH, UCN1, UCN2 AND UCN3 neuropeptides in macroendothelial cells

Gougoura Sofia , Bargiota Alexandra , Koukoulis Georgos N.

Introduction: Liraglutide treatment reduces cardiovascular complications in patients with diabetes mellitus (DM), which may imply a favorable impact on the endothelial function. The aim of the present study was to investigate in vitro the effect of liraglutide on endothelial redox balance and the parallel expression of CRH, UCN1, 2 and 3 neuropeptides, under normoglycemic and hyperglycemic conditions.Methods: Macroendothelial cell line EAhy926 w...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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